Ionic Currents during Hypoxia in Voltage- Clamped Cat Ventricular Muscle
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Ionic currents during hypoxia in voltage-clamped cat ventricular muscle.
To explore the mechanisms underlying the shortening of the cardiac action potential in hypoxia, we studied the effect of hypoxia on the ionic currents in cat papillary and trabecular muscles using the single sucrose gap-voltage clamp technique. For potentials positive to -70 mV, hypoxia induces an increase in time-independent outward current. The changes in the tail current suggest that time-de...
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